ESPN 50th Annual Meeting

ESPN 2017


 
Validation of the SphygmoCor XCEL device for central pressure measurement in children and adolescents
STELLA STABOULI 1 Chris Zervas 1 Nikoleta Printza 1 John Dotis 1 Katerina Chrysaidou 1 Olga Maliachova 1 Fotios Papachristou 1

1- 1ST DEPARTMENT OF PEDIATRICS, ARISTOTLE UNIVERSITY THESSALONIKI
 
Introduction:

Central systolic blood pressure (BP) has been increasing used in adults and seems to be superior to peripheral BP to predict cardiovascular events. The gold-standard technique is tonometry, but this technique can be challenging, especially when used on children. The purpose of this study was to validate central systolic BP assessment with novel oscillometric device (SphygmoCor XCEL) for use in children.

Material and methods:

Children and adolescents aged 5-20 years were recruited subsequently. Central systolic BP (cSPton) was measured by applanation tonometry with the “convetional” Sphygmocor device and by SphygmoCor XCEL device (cSPosc). For each patient, the average of the three recordings taken with each device was calculated. Bland-Altman plots were generated for comparison of the tonometer- to oscillometric-based method. The ANSI/AAMI/ISO for Standardization 2013 validation criteria were used to assess the accuracy of agreement between devices.

Results:

Five participants were excluded from the analysis due to low quality of recordings, four with tonometric technique and one with both devices. The remaining 67 participants had mean age 11.5±3.7 years, were 31 (46.3%) male and had mean peripheral systolic, and diastolic BP, 121.42±12.64,and 72.69±10.38 mmHg, respectively. cSPosc was strongly correlated with cSPton (R2=0.87, P<0.001). Mean cSPton was 103.23± 9.43 mmHg and mean cSPosc 103.54 ±8.87 mmHg. The mean difference between the two devices was -0.30±3.34 mmHg and fulfilled the AAMI criterion 1 (difference < 5.0 ±8.0 mmHg). The estimated s.d. (inter-subject variability) was 2.17 mmHg. Bland-Altman analysis showed good agreement with LoA -6.24 to 6.84.

Conclusions:

The new oscillometric SphygmoCor XCEL device provides equivalent results for cSP values to those obtained by tonometry in children and adolescents. Thus, the SphygmoCor XCEL device is appropriate for assessing cSP in clinical studies in the pediatric population.