ESPN 50th Annual Meeting

ESPN 2017


 
Absence of leukocytes in sediments of urine samples with positive leukocyte esterase test: Clinical predictive value
DAMLA PINAR YAVAŞ 1 SEÇIL ARSLANSOYU ÇAMLAR 2 ALPER SOYLU 2 SALIH KAVUKÇU 2

1- DOKUZ EYLUL UNIVERSITY, FACULTY OF MEDICINE, DEPARTMENT OF PEDIATRICS,IZMIR/TURKEY
2- DOKUZ EYLUL UNIVERSITY, FACULTY OF MEDICINE, DEPARTMENT OF PEDIATRICS,DIVISION OF NEPHROLOGY,IZMIR/TURKEY
 
Introduction:

 Urinary tract infection (UTI) is the second most common bacterial infection in children. False negative or positive results may occur in leukocyte esterase (LE) test which is used to determine UTI. In our study, we aimed to investigate the clinical significance of normal urine sediment findings in the presence of positive LE test in children being evaluated for UTI.

Material and methods:

 A total of 303 patients who were included in this study. Patients were divided into 2 groups: Group 1; 123 patients with a positive leukocyte esterase strip test and no pyuria in urine sediment. Group 2; 164 patients with a positive leukocyte esterase strip test and pyuria in urine sediment. Demographic characteristics, symptoms, physical findings, the presence of renal anomalies, nitrite positivity in urine, urine density, urine culture results, serum creatinine and C-reactive protein levels were recorded. 

Results:

 Group 1 included 123 patients (114 girls, 9 boys) and Group 2 included 164 patients (134 girls, 30 boys). The rate of girls in Group 1 was significantly higher than in Group 2 (p<0.001). Mean age of the girls and boys were 85.2±46.6 and 44.5±41.4 months, respectively. Physical examination revealed vulvovaginitis in 51 (44.7%) girls in Group 1 and in 41 girls (30.6%) in Group 2 (p=0.022). 

Conclusions:

 Almost half of the girls with positive urine LE test and absence of pyuria had vulvovaginits. Thus, physical examination of perineum is important in girls presenting with lower urinary tract symptoms and positive LE test.