ESPN 50th Annual Meeting

ESPN 2017


 
Renal Complications of Seasonal Influenza Virus Infections
ÖZLEM SERT 1 ELIF ÇOMAK 2 NILGÜN ERKEK 3 İMRAN SAĞLIK 4 DILEK ÇOLAK 4 DERYA MUTLU 4 GÜLŞAH KAYA AKSOY 2 MUSTAFA KOYUN 2 SEMA AKMAN 2

1- AKDENIZ UNIVERSITY SCHOOL OF MEDICINE DEPARTMENT OF PEDIATRICS
2- AKDENIZ UNIVERSITY SCHOOL OF MEDICINE DEPARTMENT OF PEDIATRIC NEPHROLOGY
3- AKDENIZ UNIVERSITY SCHOOL OF MEDICINE DEPARTMENT OF PEDIATRIC EMERGENCY CARE
4- AKDENIZ UNIVERSITY SCHOOL OF MEDICINE DEPARTMENT OF MEDICAL MICROBIOLOGY
 
Introduction:

 Renal complications of seasonal influenza A virus are uncommon and have been reported primarily as single cases or small series of patients. The aim of this study was to determine the  incidence of renal complications of seasonal influenza infections in children.

Material and methods:

 Influenza test findings in nasopharyngeal swabs, which were performed between September 2015 and March 2016 at the virology laboratory of our institution,by determining influenza antigens or using pcr method, were interpreted. The children having positive influenza test results were included in the study. The medical records of these children were evaluated retrospectively

Results:

 A total of 568 patients with positive influenza test results have been included in the study. Median age was 54.5 (1-216 ) months. 159 patients (%28.0) had an underlying chronic disease (renal, cardiac, pulmonary, haematological, oncological, endocrine, neurological, rheumatological, immunological, metabolic or genetic disease). 41 (7.2%) of them had renal complications.3 patients had acute renal failure, 2 had acute glomerulonephritis. 30 had proteinuria, 2 had isolated hematuria, and 4 had both hematuria and proteinuria. Median age of the patients with renal complications were 83.9 (7-216) months. Renal complication rate of children with underlying chronic medical condition was higher than that of patients without underlying chronic medical condition (13.8% vs 4.6%, p=0.000, OR: 3.29)] 9 patients have been followed up in intensive care unit; 2 of them had proteinuria as renal complication; one died following sepsis. 

Conclusions:

 Although most of influenza infections are selflimited, especially patients with underlying diseases are at increased risk for renal complications, which should be considered during seasonal epidemics of influenza infections.