ESPN 50th Annual Meeting

ESPN 2017


 
The role of subendocardial viability ratio and ejection duration in cardiovascular risk determination in children
NATAšA MARčUN VARDA 1 SARA NIKOLIč 1 MIRJAM MOčNIK 1

1- UNIVERSITY MEDICAL CENTRE MARIBOR
 
Introduction:

Subendocardial viability ratio (SEVR) and ejection duration (ED), parameters of pulse wave velocity, have been proposed as important factors of cardiovascular risk determination in adults. The aim of our pilot study was to investigate their role in children and adolescents with cardiovascular risk factors - hypertension, obesity and hypercholesterolemia.

 

Material and methods:

176 children and adolescents have been included in the study and divided in four groups: 31 children and adolescents with hypertension, 36 with overweight, 49 with hypertension and overweight and  70 with hypercholesterolaemia. They were compared to a control group of 50 healthy individuals. In each patient blood pressure, anthropometrical parameters, and pulse wave analysis (PWA) measurements using applanation tonometry technique were performed and calculations made, including SEVR and ER.

 

Results:

The results show a statistically significant difference in ED (p = 0.013), but not in SEVR (p = 0.074) in hypercholesterolemia group in comparison to control group. In other research groups, compared to control group, no statistically significant differences in both parameters have been found. In all study groups, SEVR correlated significantly with age and heart rate as well as with central mean pressure. In addition, the correlation between ED and both heart rate and age has also been comfirmed.

 

Conclusions:

In our pilot study the important role of SEVR and ED in early cardiovascular risk determination in children has not been confirmed. However, some results do indicate a potential role of both, at least in hypercholesterolemia, and should be further investigated.