ESPN 50th Annual Meeting

ESPN 2017


 
PARTICULAR QUALITIES OF RENAL FILTRATION FUNCTION IN CHILDREN AND ADOLESCENTS WITH OBESITY
IRINA BALALAEVA 1 TATYANA STEPANOVA 1

1- VORONEZH N.N. BURDENKO STATE MEDICAL UNIVERSITY
 
Introduction:

 The objective of this study was to determine the frequency of renal malfunctions in children and adolescents with obesity.

Material and methods:

 Glomerular filtration rate (GFR) was estimated in 76 patients with obesity, age range 5 to 17 years. Male/female - 42/34. Forty one patients had II, 31 - III, 4 - IV grade obesity. GFR was calculated by using Schwartz formula.

Results:

 In 11 patients (14.5%) GFR was increased more than 130 ml/min/1,73 m2, in 9 (11.8%) - moderately decreased < 90 ml/min/1,73 m2, but >60 ml/min/1.73 m2. The variation of GFR males had twice frequently (65%) than females. The age of the patients with decreased GFR was significantly higher (14.9±0.9 years), than in patients with increased GFR (11.0±0.9 years, ла<0.01). The elevation of GFR more often demonstrated patients with the second grade obesity (63.6%). Decreasing of GFR was not depended by the grade of obesity. 

Conclusions:

 In children and adolescents with obesity (more frequently in males) the variation of glomerular filtration rate can be noted. Obviously, initially the increasing of GFR provocated by superfluous intake of protein. With the increasing of age and obesity rate decreasing of GFR can be noted more frequently.