ESPN 50th Annual Meeting

ESPN 2017


 
Relation of renal uptake of 99mTc-DMSA to patient age
OGÜN BULBUL 1 SEÇIL ARSLANSOYU ÇAMLAR 2 AYSEGUL GEDIKLI 1 ALPER SOYLU 2 OZHAN OZDOGAN 1 SALIH KAVUKÇU 2

1- DOKUZ EYLUL UNIVERSITY, FACULTY OF MEDICINE, DEPARTMENT OF NUCLEAR MEDICINE,IZMIR/TURKEY
2- DOKUZ EYLUL UNIVERSITY, FACULTY OF MEDICINE, DEPARTMENT OF PEDIATRICS,DIVISION OF NEPHROLOGY,IZMIR/TURKEY
 
Introduction:

 99mTc-DMSA is taken up by renal proximal tubular cells and is used for renal cortical imaging. Need for proximal tubular maturation and timing of cortical scintigraphy for maximum 99mTc-DMSA uptake is not certain. We aimed to find if any relation exists between patient age and renal 99mTc-DMSA uptake.

Material and methods:

 All 99mTc-DMSA scintigraphy results were retrospectively searched by using hospital imaging database. Patients over 2 years of age at the time of scintigraphy were excluded. Patients with normal scans were identified. Timing of radiopharmaceutical injection and imaging were specified in these patients. Patients with imaging time between 2 to 4 hours of injection (n=438) were enrolled in the study. Patient age during scintigraphy was recorded as weeks or months. Age of premature patients were corrected according to their gestational age. Maximum uptakes of both kidneys on anterior and posterior views were used for calculation of geometric mean by eliminating the negative effect of the differences of the depths of kidneys. Renal uptake was calculated by dividing the maximum uptake values and geometric mean to maximum neighbouring background and maximum liver uptake.

Results:

 No significant correlation was found between renal 99mTc-DMSA uptake and patient age (r:0.001, correlation coefficient -0.19)

Conclusions:

 In the present study, no age limit regarding maximum 99mTc-DMSA uptake was determined. The test could be used in ant age period if it is indicated.