ESPN 50th Annual Meeting

ESPN 2017


 
Prevalence of Failure to Thrive in Iranian Children with Chronic Kidney Disease.
FAHIMEH SOHEILIPOUR 1 NAKYSA HOOMAN 1 PARNIAN AHMADVAND 1

1- IRAN UNIVERSITY OF MEDICAL SCIENCES,TEHRAN,IRAN
 
Introduction:

Malnutrition and inflammation are considered as risk factors of morbidity, hospitalization, and mortality in chronic kidney disease children (CKD). The aim of this study was to find the prevalence and severity of failure to thrive (FTT) in moderate to severe CKD children.

Material and methods:

 This was a cross sectional study of 84 children (30 Female, 54 male) aged 2-16 years old with CKD from June 2014 to June 2015. The inclusion criteria were eGFR less than 90 ml/min/1.73m2, being healthy in previous month of visit, having no other chronic diseases except CKD. Anthropometric data including the body mass index, height, weight, mid upper arm circumference were collected. Protein wasting energy was scored and the severity of failure to thrive estimated by Gomez and Jelliffe classifications.  P-values less than 0.05 were significant.

Results:

 Glomerulopathy and hereditary /tubulopathy constituted the main causes of underlying disease. About 79% of CKD children had FTT and this rate increased with declining of renal function (p-value< 0.05). Using modified PWE 65.5% identified to have score >=2 and it was more frequent in eGFR less than 30 (P>0.05). A quarter of patients with FTT classified as no PWE and vice versa. 

 

 

Conclusions:

 The majority of children with moderate to severe chronic kidney disease had failure to thrive and protein wasting energy. There was no correlation between inflammatory markers and the severity of CKD or the presence of failure to thrive.