ESPN 50th Annual Meeting

ESPN 2017


 
Renal cell carcinoma in a kid with transplanted kidney
SHTIZA DIAMANT 1 SHKURTI ENKELEJDA 2 BASHO MAKSIM 1 NUSHI STAVILECI VALBONA 3 PALLOSHI IRENA 4

1- UNIVERSITY HOSPITAL CENTRE MOTHER THERESA
2- UNIVERSITY OF MEDICINE
3- UNIVERSITY CLINICAL CENTER OF KOSOVA
4- PEDIATRIC DEPARTMENT, ELBASAN HOSPITAL
 
Introduction:

 Background: Renal cell carcinoma (RCC) is an uncommon renal cancer in paediatric population with the occurrence of 0.1-0.3%. Cumulative frequency 10 years subsequent to kidney transplantation is 186/100.000, in kids under the age of 18 years at the moment of transplantation. 

Material and methods:

 We would prefer to represent the case of a girl age 13 years and 5 months identified at the habitual echo-sonographic assessment seven years following kidney transplantation, with a native renal cyst. The identification of an illness that initiated the end phase renal disease was infantile steroid resistant nephritic syndrome with path histology confirmation of disseminated mesangial sclerosis established at the age of 10 months. Hemodialysis was begun at the age of three years, followed by existing allied kidney transplantation (grandfather) at the age of six. Through post-transplantation follow up there were two severe rejections, cured with metylprednisolone. 

Results:

It was detected an inadequate reaction to cure chronic allograft nephropathy built up. Six years subsequent to transplantation growth hormone (GH) therapy was begun. At the time of incidental result of kidney cyst, girl had no record of  fever, tiredness, urinary symptoms or hematuria. Magnetic resonance imaging (MRI) was carried out and left side nephrectomy was completed. Path histology demonstrated renal cell carcinoma, grade I (Fuhrman), whereas additional investigation illustrated no metastasis.

 

 

Conclusions:

 In kids with renal transplant, native renal cysts and GH therapy standard echosonographic screening of native kidneys is essential. Nephrectomy of cystic native kidneys smust be thought prior to transplantation and/or GH healing.