ESPN 50th Annual Meeting

ESPN 2017


 
Causes of Chronic Renal Insufficiency in Albanian Children
SHTIZA DIAMANT 1 SHKURTI ENKELEJDA 1 BASHO MAKSIM 1 NUSHI STAVILECI VALBONA 2 PALLOSHI IRENA 3

1- UNIVERSITY HOSPITAL CENTRE MOTHER THERESA
2- UNIVERSITY CLINICAL CENTER OF KOSOVA
3- PEDIATRIC DEPARTMENT, ELBASAN HOSPITAL
 
Introduction:

There is an increased incidence of congenital and hereditary diseases causing chronic renal failure in the pediatric age-group. To determine the major causes, clinical expression, course, and outcomes of CKD in Albanian children we conducted a prospective study from January 2015 to January 2017 in the pediatric nephrology department at the UHC “Mother Tereza” in Tirana. 

Material and methods:

This prospective study included all children (up to 15 years old) with the diagnosis of CRF who presented to the department of pediatric nephrology at the University Hospital Centre of Tirana during the period January 2015 to January 2017.  The parameters studied included: gender, age, place of residence, age at the first complaint, age when the diagnosis of CRF was made, age at which the patient reached ESRD (if applicable), family history of similar kidney diseases, consanguinity, cause of CRF, asso­ciated malformations, co-morbidity {recurrent urinary tract infections (UTI), hypertension and its response to therapy.

Results:

Forty-eight patients with varying degrees of renal impairment were involved in the analysis. A total of 27 children (56%) had obstructive nephropathy (ON) as the cause of chronic renal insufficiency and 21 children (44%) had non-obstructive nephropathy (Non-ON). Neurogenic bladder was the commonest cause of ON, seen in 13 patients (27%), nephrolithiasis was seen in 9 patients (19%), urethral stenosis in three (6%), Uretro-Pelvie Junction (UPJ) stenosis in one (2%), and posterior urethral valves in one case (2%). 

Conclusions:

In our study obstructive nephropathy has been shown to be the most important cause of CKD. Whether this is due to a true higher prevalence of some causes of obstructive nephropathy or an insufficient sample size, can only be elucidated with further studies involving larger number of patients.